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VEGF receptor signalling in vertebrate development

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dc.contributor.authorVieira, J.
dc.contributor.authorRuhrberg, C.
dc.contributor.authorSchwarz, Q.
dc.date.issued2010
dc.descriptionLink to a related website: http://europepmc.org/articles/pmc2901813?pdf=render, Open Access via Unpaywall
dc.description.abstractThe secreted glycoprotein vascular endothelial growth factor A (VEGF or VEGFA) affects many different cell types and modifies a wide spectrum of cellular behaviors in tissue culture models, including proliferation, migration, differentiation and survival. The versatility of VEGF signaling is reflected in the complex composition of its cell surface receptors and their ability to activate a variety of different downstream signaling molecules. A major challenge for VEGF research is to determine which of the specific signaling pathways identified in vitro control development and homeostasis of tissues containing VEGF-responsive cell types in vivo.
dc.description.statementofresponsibilityJoaquim Miguel Vieira, Christiana Ruhrberg and Quenten Schwarz
dc.description.urihttp://www.mendeley.com/research/vegf-receptor-signalling-in-vertebrate-development/
dc.identifier.citationOrganogenesis, 2010; 6(2):97-106
dc.identifier.doi10.4161/org.6.2.11686
dc.identifier.issn1547-6278
dc.identifier.issn1555-8592
dc.identifier.urihttp://hdl.handle.net/2440/66058
dc.language.isoen
dc.publisherLandes Bioscience
dc.rightsCopyright © 2010 Landes Bioscience
dc.source.urihttps://doi.org/10.4161/org.6.2.11686
dc.subjectVEGF
dc.subjectVEGFR1
dc.subjectVEGFR2
dc.subjectFLT1
dc.subjectKDR
dc.subjectFLK1
dc.subjectneuropilin
dc.subjectHSPG
dc.titleVEGF receptor signalling in vertebrate development
dc.typeJournal article
pubs.publication-statusPublished

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