Preparation of (–)-(7R)-7-acetyl-7-hydroxy-4,4-dimethoxy-5,6,7,8-tetrahydro-naphthalen-1(4H)-one, a chiral AB-synthon for anthracycline synthesis

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dc.contributor.authorWarrener, R.N.
dc.contributor.authorGee, P.S.
dc.contributor.authorRussell, R.A.
dc.date.issued1981
dc.description.abstractThe (–)-(R)-dienone (13) was prepared in 10 steps from the known 8-hydroxy-5-methoxy-2, 3-dihydronaphthalen-1(4H)-one (2), and the chirality at C(7) in (13) corresponds to that found at C(9) in the naturally occurring anthracyclines related to daunomycin.
dc.description.statementofresponsibilityRonald N. Warrener, Paul S. Gee and Richard A. Russell
dc.identifier.citationJournal of the Chemical Society, Chemical Communications, 1981; 1981(21):1100-1101
dc.identifier.doi10.1039/c39810001100
dc.identifier.issn0022-4936
dc.identifier.urihttp://hdl.handle.net/2440/85911
dc.language.isoen
dc.publisherRoyal Society of Chemistry
dc.rightsCopyright status unknown
dc.source.urihttps://doi.org/10.1039/c39810001100
dc.titlePreparation of (–)-(7R)-7-acetyl-7-hydroxy-4,4-dimethoxy-5,6,7,8-tetrahydro-naphthalen-1(4H)-one, a chiral AB-synthon for anthracycline synthesis
dc.typeJournal article
pubs.publication-statusPublished

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