Initial trends in quality of life and survival in CAL patients on domiciliary oxygen therapy

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dc.contributor.authorCrockett, A.
dc.contributor.authorCranston, J.
dc.contributor.authorMoss, J.
dc.contributor.authorAlpers, J.
dc.date.issued1996
dc.description.abstractDomiciliary oxygen therapy has become a major form of treatment for chronic airflow limitation (CAL), and has been demonstrated to increase survival and reduce hospitalization. The impact of long-term domiciliary oxygen therapy on health-related quality of life is less clear. This study was conducted to document prospectively the quality of life and survival of patients with CAL after being prescribed domiciliary oxygen therapy at the Flinders Medical Centre in South Australia. The study sample consisted of 57 adult patients (29 males and 28 females, aged 80 yrs or less) with severe CAL referred to the Respiratory Unit for domiciliary oxygen therapy. Prior to the commencement of oxygen therapy, baseline physiological assessment was performed and the Nottingham Health Profile (NHP), the Chronic Respiratory Disease Questionnaire (CRDQ), a Quality of Life Thermometer (QOLTH) and Life Satisfaction Index (LSI) were used to measure the health-related quality of life (HR-QOL). Follow-ups occurred at 3 and 6 months after the commencement of home oxygen therapy. Quality of life at baseline was not correlated with the physiological parameters of lung function and blood gas analysis. However, considerable correlation was found between two of the quality of life instruments used. The female patients on home oxygen therapy experienced some improvement in several dimensions of quality of life measured by the instruments. The observations were less clearcut for males. By the time the patients' physiological and clinical condition has deteriorated for them to fulfil prescription guidelines for home oxygen therapy, patients with chronic airflow limitation are experiencing a marked reduction in quality of life. However, the strength of the reported findings must be tempered by remaining questions over the validity of the instruments and their responsiveness to change; and by the small number of enrolments so far, and the relatively short period of follow-up.
dc.identifier.citationMonaldi Archives for Chest Disease, 1996; 51(1):64-71
dc.identifier.issn1122-0643
dc.identifier.issn2532-5264
dc.identifier.orcidMoss, J. [0000-0003-4216-1761]
dc.identifier.urihttp://hdl.handle.net/2440/4228
dc.language.isoen
dc.publisherFondazione clinica del lavoro edizioni
dc.subjectHumans
dc.subjectLung Diseases, Obstructive
dc.subjectPulmonary Ventilation
dc.subjectPrognosis
dc.subjectOxygen Inhalation Therapy
dc.subjectSurvival Rate
dc.subjectLongitudinal Studies
dc.subjectFollow-Up Studies
dc.subjectProspective Studies
dc.subjectPatient Compliance
dc.subjectSex Distribution
dc.subjectQuality of Life
dc.subjectAged
dc.subjectAged, 80 and over
dc.subjectHome Care Services
dc.subjectAustralia
dc.subjectFemale
dc.subjectMale
dc.titleInitial trends in quality of life and survival in CAL patients on domiciliary oxygen therapy
dc.typeJournal article
pubs.publication-statusPublished

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