Indicators of early change in cognitive behaviour therapy that predict eating disorder remission

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dc.contributor.authorWade, T.D.
dc.contributor.authorGeorgiou, N.
dc.contributor.authorKeegan, E.
dc.contributor.authorPellizzer, M.L.
dc.contributor.authorWaller, G.
dc.date.issued2025
dc.description.abstractWe examined the utility of three definitions of rapid response to treatment for predicting remission in a transdiagnostic sample receiving 10-session cognitive behaviour therapy (CBT) for an eating disorder. Both efficiency (categorising the greatest number of people as rapid responders) and predictiveness (performs best in predicting outcomes) were compared. The participants (N = 176, 93 % female, 89 % white, mean age 26.65 years) completed measures at baseline and before session 4 of CBT which was used to calculate rapid response. Remission was achieved by 64 participants (36 %) at the end of therapy. A multivariable logistic regression analysis was used to examine the contribution of rapid response, as well as baseline disordered eating, impairment, general negative emotion, to remission status. Two of the rapid response definitions were associated with participants being 2.5 times more likely to achieve remission at end of treatment. In both cases, remission was also associated with a lower level of baseline eating disorder psychopathology. The preferred definition (a reduction of ≥1.13 points on the Eating Disorder Examination Questionnaire) categorised 58 % of participants as rapid responders. These findings can be used to inform clinicians of meaningful early change that predicts positive outcomes in brief CBT for eating disorders. Early change indicators can inform collaborative consideration of barriers to progress and approaches to tackle these, making CBT more effective for more people. The conclusions should be interpreted with caution given remission was only examined at end of treatment and not over longer-term follow-up.
dc.description.statementofresponsibilityTracey D. Wade, Neophytos Georgiou, Ella Keegan, Mia L. Pellizzer, Glenn Waller
dc.identifier.citationBehaviour Research and Therapy, 2025; 190:104754-1-104754-5
dc.identifier.doi10.1016/j.brat.2025.104754
dc.identifier.issn0005-7967
dc.identifier.issn1873-622X
dc.identifier.orcidGeorgiou, N. [0000-0002-7868-8250]
dc.identifier.urihttps://hdl.handle.net/2440/147695
dc.language.isoen
dc.publisherElsevier
dc.relation.granthttp://purl.org/au-research/grants/nhmrc/2025665
dc.rights© 2025 The Authors. Published by Elsevier Ltd. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
dc.source.urihttps://doi.org/10.1016/j.brat.2025.104754
dc.subjectRemission; Eating disorder; Rapid response; Treatment; Transdiagnostic
dc.subject.meshHumans
dc.subject.meshTreatment Outcome
dc.subject.meshRemission Induction
dc.subject.meshAdult
dc.subject.meshMiddle Aged
dc.subject.meshFemale
dc.subject.meshMale
dc.subject.meshYoung Adult
dc.subject.meshFeeding and Eating Disorders
dc.subject.meshCognitive Behavioral Therapy
dc.titleIndicators of early change in cognitive behaviour therapy that predict eating disorder remission
dc.typeJournal article
pubs.publication-statusPublished

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