Analysis of datasets showing which compounds kill which organisms: inferring two systems

Hutchinson, T.

doi:10.1016/j.ejmech.2003.11.006

Analysis of datasets showing which compounds kill which organisms: inferring two systems

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2004

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Hutchinson, T.

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Journal article

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European Journal of Medicinal Chemistry, 2004; 39(1):107-111

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T. P. Hutchinson

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10.1016/j.ejmech.2003.11.006

Abstract

Experiments are sometimes conducted to show which of several compounds is successful at inactivating which of several microorganisms. This paper proposes a method of analysing the datasets obtained. The example refers to 33 compounds (2,4-dihydroxythiobenzanilides) and seven microorganisms (dermatophytes) [data from Eur. J. Med. Chem. 35 (2000) 393]. The conclusion is that two systems or modes of action are needed to explain the data.

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https://doi.org/10.1016/j.ejmech.2003.11.006

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http://hdl.handle.net/2440/36426

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Analysis of datasets showing which compounds kill which organisms: inferring two systems

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