The Performance of Freestyle Libre Pro Flash Continuous Glucose Monitoring in Hospitalized Patients Treated with an Intravenous Insulin Infusion for Acute Prednisolone-Induced Hyperglycemia

dc.contributor.authorChen, A.X.
dc.contributor.authorRadhakutty, A.
dc.contributor.authorZimmermann, A.
dc.contributor.authorStranks, S.N.
dc.contributor.authorThompson, C.H.
dc.contributor.authorBurt, M.G.
dc.date.issued2024
dc.description.abstractFew studies have evaluated the performance of flash glucose monitoring in hospitalized patients requiring intravenous insulin therapy. In this prospective study, an intravenous insulin infusion was adjusted hourly using flash glucose monitoring in hospitalized adults with prednisolone-associated hyperglycemia. The difference in paired point of care (POC) and flash glucose measurements and risk of severe hyper- or hypoglycemia (assessed by Clarke error grid analysis) were assessed. Glucose concentration measured by flash glucose monitoring was lower than POC glucose (mean difference 1.5 mmol/L [27 mg/dL], p < 0.001); however, mean POC glucose was within the target range (9.1 ± 4.1 mmol/L [164 ± 72 mg/dL]) and 97.8% of glucose measurements were within Zone A and B on error grid analysis. Flash glucose monitoring could be used in combination with POC glucose monitoring to minimize the frequency of finger prick blood glucose levels in hospitalized patients prescribed an intravenous insulin infusion.
dc.description.statementofresponsibilityAngela X. Chen, Anjana Radhakutty, Anthony Zimmermann, Stephen N. Stranks, Campbell H. Thompson, and Morton G. Burt
dc.identifier.citationDiabetes Technology and Therapeutics, 2024; 26(1):76-79
dc.identifier.doi10.1089/dia.2023.0360
dc.identifier.issn1520-9156
dc.identifier.issn1520-9156
dc.identifier.orcidThompson, C.H. [0000-0002-5164-3327]
dc.identifier.urihttps://hdl.handle.net/2440/141791
dc.language.isoen
dc.publisherMary Ann Liebert
dc.relation.granthttp://purl.org/au-research/grants/nhmrc/GNT1189788
dc.rightsCopyright © 2024, Mary Ann Liebert, Inc.
dc.source.urihttp://dx.doi.org/10.1089/dia.2023.0360
dc.subjectglucose monitoring; insulin infusion
dc.subject.meshHumans
dc.subject.meshHyperglycemia
dc.subject.meshPrednisolone
dc.subject.meshInsulin
dc.subject.meshBlood Glucose
dc.subject.meshBlood Glucose Self-Monitoring
dc.subject.meshProspective Studies
dc.subject.meshAdult
dc.subject.meshInsulin, Regular, Human
dc.subject.meshContinuous Glucose Monitoring
dc.titleThe Performance of Freestyle Libre Pro Flash Continuous Glucose Monitoring in Hospitalized Patients Treated with an Intravenous Insulin Infusion for Acute Prednisolone-Induced Hyperglycemia
dc.typeJournal article
pubs.publication-statusPublished

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