Antibody immobilization within glass microstructured fibers: A route to sensitive and selective biosensors

Simple item page
dc.contributor.authorRuan, Y.
dc.contributor.authorFoo, H.
dc.contributor.authorWarren-Smith, S.
dc.contributor.authorHoffmann, P.
dc.contributor.authorMoore, R.
dc.contributor.authorEbendorff-Heidepriem, H.
dc.contributor.authorMonro, T.
dc.date.issued2008
dc.description.abstractGlass microstructured optical fibers have been rendered biologically active for the first time via the immobilization of antibodies within the holes in the fiber cross-section. This has been done by introducing coating layers to the internal surfaces of soft glass fibers. The detection of proteins that bind to these antibodies has been demonstrated experimentally within this system via the use of fluorescence labeling. The approach combines the sensitivity resulting from the long interaction lengths of filled fibers with the selectivity provided by the use of antibodies.
dc.description.statementofresponsibilityYinlan Ruan, Tze Cheung Foo, Stephen Warren-Smith, Peter Hoffmann, Roger C. Moore, Heike Ebendorff-Heidepriem, Tanya M. Monro
dc.identifier.citationOptics Express, 2008; 16(22):18514-18523
dc.identifier.doi10.1364/OE.16.018514
dc.identifier.issn1094-4087
dc.identifier.issn1094-4087
dc.identifier.orcidWarren-Smith, S. [0000-0002-2612-6344]
dc.identifier.orcidEbendorff-Heidepriem, H. [0000-0002-4877-7770]
dc.identifier.urihttp://hdl.handle.net/2440/47928
dc.language.isoen
dc.publisherOptical Soc Amer
dc.relation.granthttp://purl.org/au-research/grants/arc/DP0665486
dc.rights© 2008 Optical Society of America
dc.source.urihttps://doi.org/10.1364/oe.16.018514
dc.subjectGlass
dc.subjectAntibodies
dc.subjectAntigen-Antibody Complex
dc.subjectSolutions
dc.subjectBiosensing Techniques
dc.subjectFluorescence
dc.titleAntibody immobilization within glass microstructured fibers: A route to sensitive and selective biosensors
dc.typeJournal article
pubs.publication-statusPublished

Files

Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
hdl_47928.pdf
Size:
568.39 KB
Format:
Adobe Portable Document Format
Description:
Published version
Download

Collections

IPAS publications
Centre of Expertise in Photonics publications