Evaluation of the Becton Dickinson Directigen test for respiratory syncytial virus in nasopharyngeal aspirates
Date
1990
Authors
Kok, T.
Barancek, K.
Burrell, C.
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Journal article
Citation
Journal of Clinical Microbiology, 1990; 28(6):1458-1459
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Tuckweng Kok, Kristina Barancek, and Christopher J. Burrell
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Abstract
A premarket trial of the Becton Dickinson Directigen respiratory syncytial virus membrane-based enzyme immunoassay compared the test with virus isolation for the detection of respiratory syncytial virus in 583 nasopharyngeal aspirates. After modification, the Directigen test showed a sensitivity of 83% and a specificity of 90%. It offers the potential for an efficient bedside test--without the need for any equipment--for the diagnosis of respiratory syncytial virus infection and requires only a 0.25-ml sample volume. However, for optimum reliability, freezing-thawing of samples and access to a confirmatory test were shown to be necessary.
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Copyright © 1990, American Society for Microbiology