Evaluation of the Becton Dickinson Directigen test for respiratory syncytial virus in nasopharyngeal aspirates

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dc.contributor.authorKok, T.
dc.contributor.authorBarancek, K.
dc.contributor.authorBurrell, C.
dc.date.issued1990
dc.description.abstractA premarket trial of the Becton Dickinson Directigen respiratory syncytial virus membrane-based enzyme immunoassay compared the test with virus isolation for the detection of respiratory syncytial virus in 583 nasopharyngeal aspirates. After modification, the Directigen test showed a sensitivity of 83% and a specificity of 90%. It offers the potential for an efficient bedside test--without the need for any equipment--for the diagnosis of respiratory syncytial virus infection and requires only a 0.25-ml sample volume. However, for optimum reliability, freezing-thawing of samples and access to a confirmatory test were shown to be necessary.
dc.description.statementofresponsibilityTuckweng Kok, Kristina Barancek, and Christopher J. Burrell
dc.identifier.citationJournal of Clinical Microbiology, 1990; 28(6):1458-1459
dc.identifier.doi10.1128/jcm.28.6.1458-1459.1990
dc.identifier.issn0095-1137
dc.identifier.issn1098-660X
dc.identifier.orcidBurrell, C. [0000-0002-4020-349X]
dc.identifier.urihttp://hdl.handle.net/2440/114997
dc.language.isoen
dc.publisherAmerican Society for Microbiology
dc.rightsCopyright © 1990, American Society for Microbiology
dc.source.urihttps://jcm.asm.org/content/28/6/1458
dc.subjectNasopharynx
dc.subjectCells, Cultured
dc.subjectAnimals
dc.titleEvaluation of the Becton Dickinson Directigen test for respiratory syncytial virus in nasopharyngeal aspirates
dc.typeJournal article
pubs.publication-statusPublished

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