Detection of quantum-dot labeled proteins using soft glass microstructured optical fibers

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dc.contributor.authorRuan, Y.
dc.contributor.authorSchartner, E.
dc.contributor.authorEbendorff-Heidepriem, H.
dc.contributor.authorHoffmann, P.
dc.contributor.authorMonro, T.
dc.date.issued2007
dc.descriptionThis paper was published in Optics Express and is made available as an electronic reprint with the permission of OSA. The paper can be found at the following URL on the OSA website: http://www.opticsinfobase.org/abstract.cfm?URI=oe-15-26-17819. Systematic or multiple reproduction or distribution to multiple locations via electronic or other means is prohibited and is subject to penalties under law.
dc.description.abstractThe detection of quantum-dot labeled proteins is demonstrated within lead silicate soft glass microstructured optical fibers using near infrared light. The protein concentration is measured using a new fluorescence capture approach. Light guided within the fiber is used both to excite and collect fluorescent photons, and the detection limit achieved without optimization of the fiber geometry is 1 nM, using just 3% of the guided mode of the fiber. Issues that currently restrict the detection of lower protein concentrations are discussed.
dc.description.statementofresponsibilityYinlan Ruan, Erik P. Schartner, Heike Ebendorff-Heidepriem, Peter Hoffmann and Tanya M. Monro
dc.identifier.citationOptics Express, 2007; 15(26):17819-17826
dc.identifier.doi10.1364/OE.15.017819
dc.identifier.issn1094-4087
dc.identifier.issn1094-4087
dc.identifier.orcidSchartner, E. [0000-0003-1669-4302]
dc.identifier.orcidEbendorff-Heidepriem, H. [0000-0002-4877-7770]
dc.identifier.urihttp://hdl.handle.net/2440/44156
dc.language.isoen
dc.publisherOptical Soc Amer
dc.rightsCopyright © 2007 Optical Society of America
dc.source.urihttp://www.opticsinfobase.org/abstract.cfm?URI=oe-15-26-17819
dc.subjectGlass
dc.subjectProteins
dc.subjectLuminescent Measurements
dc.subjectSpectrometry, Fluorescence
dc.subjectSensitivity and Specificity
dc.subjectReproducibility of Results
dc.subjectEquipment Design
dc.subjectEquipment Failure Analysis
dc.subjectQuantum Dots
dc.subjectComputer-Aided Design
dc.subjectFiber Optic Technology
dc.subjectElastic Modulus
dc.titleDetection of quantum-dot labeled proteins using soft glass microstructured optical fibers
dc.typeJournal article
pubs.publication-statusPublished

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