Current studentsExisting staffContact us
 

Investigating the appearance of new psychoactive substances in South Australia using wastewater and forensic data

Simple item page
dc.contributor.authorBade, R.
dc.contributor.authorStockham, P.
dc.contributor.authorPainter, B.
dc.contributor.authorCelma, A.
dc.contributor.authorBijlsma, L.
dc.contributor.authorHernandez, F.
dc.contributor.authorWhite, J.M.
dc.contributor.authorGerber, C.
dc.date.issued2019
dc.descriptionData source: Supporting Information, https://doi.org/10.1002/dta.2484 Link to a related website: http://repositori.uji.es/xmlui/bitstream/10234/180982/1/Bade_2018_Investigating.pdf, Open Access via Unpaywall
dc.description.abstractNew psychoactive substances (NPS) have increased in use and popularity worldwide. Wastewater analysis has been successfully applied to evaluate illicit drugs use within a population. However, for NPS, such approach may be limited due to low doses of NPS combined with their ever‐changing composition and usage. The dynamic nature of the NPS market means use may be opportunistic, infrequent and with few users. Hence, the use of complementary information sources is recommended to improve the knowledge on NPS consumption. The aim of this study was to investigate the changing landscape of NPS use on a community scale by combining wastewater analysis and forensic toxicology. Forensic analysis provided specific information on NPS prevalence in post‐mortem blood samples in Adelaide, South Australia over five years, while wastewater analysis showed community use over the same period. A qualitative liquid chromatography‐high resolution mass spectrometry method was initially used to screen the wastewater samples. A total of 24 NPS were found: six in wastewater only, 13 in forensic post mortem toxicology samples only and five in both. As these results showed the presence of NPS, a targeted method was subsequently employed to quantify levels of these NPS in wastewater. Temporal trends were found in wastewater with distinct tendencies for synthetic cathinones visible over the period studied.
dc.identifier.citationDrug Testing and Analysis, 2019; 11(2):250-256
dc.identifier.doi10.1002/dta.2484
dc.identifier.issn1942-7603
dc.identifier.issn1942-7611
dc.identifier.urihttps://hdl.handle.net/11541.2/134030
dc.language.isoen
dc.publisherWiley
dc.relation.fundingSA Health
dc.relation.fundingGeneralitat Valenciana 2014/023 Prometeo II
dc.relation.fundingSpanish Ministry of Economy and Competitiveness , Project: CTQ2015-65603
dc.relation.fundingThyne Reid Foundation
dc.relation.fundingUniversity of South Australia Early Career Researcher International Travel Grant
dc.rightsCopyright 2018 Wiley
dc.source.urihttps://doi.org/10.1002/dta.2484
dc.subjectsynthetic cathinones
dc.subjecthigh resolution mass spectrometry
dc.subjecttriple quadrupole
dc.subjectwastewater
dc.subjectforensic toxicology
dc.titleInvestigating the appearance of new psychoactive substances in South Australia using wastewater and forensic data
dc.typeJournal article
pubs.publication-statusPublished
ror.mmsid9916230000601831

Files

Collections