Mindfulness training does not reduce inflammatory cytokine levels in chronic tension-type headache
Date
2013
Authors
Cathcart, S.
Barone, V.
Immink, M.
Proeve, M.
Hayball, J.
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Journal article
Citation
Journal of Pain Management, 2013; 6(3):235-238
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Stuart Cathcart, Chris Della Vedova, Maarten Immink, Michael Proeve, and John Hayball
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Abstract
Aim: To examine effects of mindfulness training on serum proinflammatory cytokine levels in chronic tension-type headache (CTH) sufferers.
Method: Forty-three CTH sufferers participated in a randomized wait-list controlled trial of a mindfulness intervention for headache. Serum concentrations of cytokines IL1-β, IL-2, IL-6, IL-8, IL-12, IL-18, IFN-γ, MCP-1 and TNF-α were measured before and after treatment/wait-list control conditions.
Results: Repeated Measures Analysis of Variance revealed that IL1-β, IL-6, IL-8, MCP-1 and TNF-α decreased from pre to post assessments in the treatment and wait-list groups, with no group or group x time effects.
Conclusions: Mindfulness training compared to a wait-list control condition does not reduce serum cytokine levels in CTH sufferers.
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