Altered Insulin-Like Growth Factor binding Proteins
| dc.contributor.assignee | University of Adelaide | |
| dc.contributor.author | Forbes, B. | |
| dc.contributor.other | Foley & Lardner LLP | |
| dc.date.issued | 2009 | |
| dc.description | PATENT: B. Forbes (Assignee: University of Adelaide). US 7488798 (PCT/AU03/00898) filed Jul 11, 2003; published Feb 10, 2009; predicted expiry Jul 11, 2023. | |
| dc.description.abstract | Altered IGFBPs are able to bind IGF, but the release is inhibited by resistance to protease cleavage and/or reduced binding to extracellular matrix (ECM). Alterations have been made in IGFBP-2 to the linker domain in particular and to two amino acid motifs found to be important for ECM binding. IGF-1 mediated proliferation of cancer cells have been inhibited by use of the altered IGFBPs. | |
| dc.description.statementofresponsibility | Inventor B. Forbes; Assigned to University of Adelaide; Foley & Lardner LLP agents for inventor. | |
| dc.description.uri | http://www.patentlens.net/patentlens/patent/US_7488798/en/ | |
| dc.identifier.patent | 7488798 | |
| dc.identifier.uri | http://hdl.handle.net/2440/74682 | |
| dc.language.iso | en | |
| dc.subject | US 7488798 | |
| dc.subject | PCT/AU03/00898 | |
| dc.title | Altered Insulin-Like Growth Factor binding Proteins | |
| dc.type | Patent | |
| pubs.publication-status | Published |