Current studentsExisting staffContact us
 

What do clinical practice guidelines say about deprescribing? A scoping review

Simple item page
dc.contributor.authorLangford, A.V.
dc.contributor.authorWarriach, I.
dc.contributor.authorMcEvoy, A.M.
dc.contributor.authorKaraim, E.
dc.contributor.authorChand, S.
dc.contributor.authorTurner, J.P.
dc.contributor.authorThompson, W.
dc.contributor.authorFarrell, B.J.
dc.contributor.authorPollock, D.
dc.contributor.authorMoriarty, F.
dc.contributor.authorGnjidic, D.
dc.contributor.authorAilabouni, N.J.
dc.contributor.authorReeve, E.
dc.date.issued2025
dc.descriptionPublished Online First 24 May 2024 Data source: Supplementary materials, https://doi.org/10.1136/bmjqs-2024-017101
dc.description.abstractIntroduction Deprescribing (medication dose reduction or cessation) is an integral component of appropriate prescribing. The extent to which deprescribing recommendations are included in clinical practice guidelines is unclear. This scoping review aimed to identify guidelines that contain deprescribing recommendations, qualitatively explore the content and format of deprescribing recommendations and estimate the proportion of guidelines that contain deprescribing recommendations. Methods Bibliographic databases and Google were searched for guidelines published in English from January 2012 to November 2022. Guideline registries were searched from January 2017 to February 2023. Two reviewers independently screened records from databases and Google for guidelines containing one or more deprescribing recommendations. A 10% sample of the guideline registries was screened to identify eligible guidelines and estimate the proportion of guidelines containing a deprescribing recommendation. Guideline and recommendation characteristics were extracted and language features of deprescribing recommendations including content, form, complexity and readability were examined using a conventional content analysis and the SHeLL Health Literacy Editor tool. Results 80 guidelines containing 316 deprescribing recommendations were included. Deprescribing recommendations had substantial variability in their format and terminology. Most guidelines contained recommendations regarding for who (75%, n=60), what (99%, n=89) and when or why (91%, n=73) to deprescribe, however, fewer guidelines (58%, n=46) contained detailed guidance on how to deprescribe. Approximately 29% of guidelines identified from the registries sample (n=14/49) contained one or more deprescribing recommendations. Conclusions Deprescribing recommendations are increasingly being incorporated into guidelines, however, many guidelines do not contain clear and actionable recommendations on how to deprescribe which may limit effective implementation in clinical practice. A co-designed template or best practice guide, containing information on aspects of deprescribing recommendations that are essential or preferred by endusers should be developed and employed.
dc.description.statementofresponsibilityAili Veronica Langford, Imaan Warriach, Aisling M McEvoy, Elisa Karaim, Shyleen Chand, Justin P Turner, Wade Thompson, Barbara J Farrell, Danielle Pollock, Frank Moriarty, Danijela Gnjidic, Nagham J Ailabouni, Emily Reeve
dc.identifier.citationBMJ Quality and Safety, 2025; 34(1):017101-1-017101-12
dc.identifier.doi10.1136/bmjqs-2024-017101
dc.identifier.issn1475-3898
dc.identifier.issn1475-3898
dc.identifier.orcidPollock, D. [0000-0002-6604-0609]
dc.identifier.urihttps://hdl.handle.net/2440/142775
dc.language.isoen
dc.publisherBMJ Publishing Group
dc.relation.granthttp://purl.org/au-research/grants/nhmrc/1195460
dc.relation.granthttp://purl.org/au-research/grants/nhmrc/2025289
dc.rights© Author(s) (or their employer(s)) 2024. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.
dc.source.urihttps://qualitysafety.bmj.com/content/early/2024/05/24/bmjqs-2024-017101
dc.subjectClinical pharmacology
dc.subjectClinical practice guidelines
dc.subjectMedication safety
dc.titleWhat do clinical practice guidelines say about deprescribing? A scoping review
dc.typeJournal article
pubs.publication-statusPublished

Files

Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
hdl_142775.pdf
Size:
1.34 MB
Format:
Adobe Portable Document Format
Description:
Published version
Download

Collections

Research Outputs