Phylogenetic analysis of Porphyromonas species isolated from the oral cavity of Australian marsupials
Date
2008
Authors
Mikkelsen, D.
Milinovich, G.
Burrell, P.
Huynh, S.
Pettett, L.
Blackall, L.
Trott, D.
Bird, P.
Editors
Advisors
Journal Title
Journal ISSN
Volume Title
Type:
Journal article
Citation
Environmental Microbiology, 2008; 10(9):2425-2432
Statement of Responsibility
Deirdre Mikkelsen, Gabriel J. Milinovich, Paul C. Burrell, Sharnan C. Huynh, Lyndall M. Pettett, Linda L. Blackall, Darren J. Trott and Philip S. Bird
Conference Name
Abstract
Porphyromonas species are frequently isolated from the oral cavity and are associated with periodontal disease in both animals and humans. Black, pigmented Porphyromonas spp. isolated from the gingival margins of selected wild and captive Australian marsupials with varying degrees of periodontal disease (brushtail possums, koalas and macropods) were compared phylogenetically to Porphyromonas strains from non-marsupials (bear, wolf, coyote, cats and dogs) and Porphyromonas gingivalis strains from humans using 16S rRNA gene sequence analysis. The results of the phylogenetic analysis identified three distinct groups of strains. A monophyletic P. gingivalis group (Group 1) contained only strains isolated from humans and a Porphyromonas gulae group (Group 2) was divided into three distinct subclades, each containing both marsupial and non-marsupial strains. Group 3, which contained only marsupial strains, including all six strains isolated from captive koalas, was genetically distinct from P. gulae and may constitute a new Porphyromonas species.
School/Discipline
Dissertation Note
Provenance
Description
Access Status
Rights
© 2008 The Authors