Phylogenetic analysis of Porphyromonas species isolated from the oral cavity of Australian marsupials

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dc.contributor.authorMikkelsen, D.
dc.contributor.authorMilinovich, G.
dc.contributor.authorBurrell, P.
dc.contributor.authorHuynh, S.
dc.contributor.authorPettett, L.
dc.contributor.authorBlackall, L.
dc.contributor.authorTrott, D.
dc.contributor.authorBird, P.
dc.date.issued2008
dc.description.abstractPorphyromonas species are frequently isolated from the oral cavity and are associated with periodontal disease in both animals and humans. Black, pigmented Porphyromonas spp. isolated from the gingival margins of selected wild and captive Australian marsupials with varying degrees of periodontal disease (brushtail possums, koalas and macropods) were compared phylogenetically to Porphyromonas strains from non-marsupials (bear, wolf, coyote, cats and dogs) and Porphyromonas gingivalis strains from humans using 16S rRNA gene sequence analysis. The results of the phylogenetic analysis identified three distinct groups of strains. A monophyletic P. gingivalis group (Group 1) contained only strains isolated from humans and a Porphyromonas gulae group (Group 2) was divided into three distinct subclades, each containing both marsupial and non-marsupial strains. Group 3, which contained only marsupial strains, including all six strains isolated from captive koalas, was genetically distinct from P. gulae and may constitute a new Porphyromonas species.
dc.description.statementofresponsibilityDeirdre Mikkelsen, Gabriel J. Milinovich, Paul C. Burrell, Sharnan C. Huynh, Lyndall M. Pettett, Linda L. Blackall, Darren J. Trott and Philip S. Bird
dc.identifier.citationEnvironmental Microbiology, 2008; 10(9):2425-2432
dc.identifier.doi10.1111/j.1462-2920.2008.01668.x
dc.identifier.issn1462-2912
dc.identifier.issn1462-2920
dc.identifier.orcidTrott, D. [0000-0002-8297-5770]
dc.identifier.urihttp://hdl.handle.net/2440/66056
dc.language.isoen
dc.publisherBlackwell Science Ltd
dc.rights© 2008 The Authors
dc.source.urihttps://doi.org/10.1111/j.1462-2920.2008.01668.x
dc.subjectMouth
dc.subjectAnimals
dc.subjectMarsupialia
dc.subjectHumans
dc.subjectPorphyromonas
dc.subjectBacterial Infections
dc.subjectPeriodontal Diseases
dc.subjectDNA, Bacterial
dc.subjectRNA, Ribosomal, 16S
dc.subjectBacterial Typing Techniques
dc.subjectPolymerase Chain Reaction
dc.subjectSequence Analysis, DNA
dc.subjectPhylogeny
dc.subjectGenes, rRNA
dc.subjectMolecular Sequence Data
dc.subjectAustralia
dc.titlePhylogenetic analysis of Porphyromonas species isolated from the oral cavity of Australian marsupials
dc.typeJournal article
pubs.publication-statusPublished

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