Amino-LNA, Thio-LNA and α-L-Oxy-LNA
Date
2004
Authors
Thrue, Charlotte Albaek
Rosenbohm, Christoph
Hansen, Henrik Frydenlund
Westergaard, Majken
Mikkelsen, Nikolaj Dam
Christensen, Signe M.
Koch, Troels
Pedersen, Daniel Sejer
Frieden, Miriam
Editors
Advisors
Journal Title
Journal ISSN
Volume Title
Type:
Patent
Citation
Statement of Responsibility
Conference Name
Abstract
A novel class of pharmaceuticals which comprises a Locked Nucleic Acid (LNA) which can be used in antisense therapy. These novel oligonucleotides have improved antisense properties. The novel oligonucleotides are composed of at least one LNA selected from beta-D-thio/amino-LNA or alpha-L-oxy/thio/amino-LNA. The oligonucleotides comprising LNA may also include DNA and/or RNA nucleotides
School/Discipline
School of Chemistry and Physics : Chemistry
Dissertation Note
Provenance
Description
Pub. No.: WO/2004/046160 International Application No.: PCT/DK2003/000788
Publication Date: 03.06.2004 International Filing Date: 18.11.2003
Chapter 2 Demand Filed: 08.06.2004
IPC: A61K 31/7088 (2006.01)