Amino-LNA, Thio-LNA and α-L-Oxy-LNA

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dc.contributor.authorThrue, Charlotte Albaeken
dc.contributor.authorRosenbohm, Christophen
dc.contributor.authorHansen, Henrik Frydenlunden
dc.contributor.authorWestergaard, Majkenen
dc.contributor.authorMikkelsen, Nikolaj Damen
dc.contributor.authorChristensen, Signe M.en
dc.contributor.authorKoch, Troelsen
dc.contributor.authorPedersen, Daniel Sejeren
dc.contributor.authorFrieden, Miriamen
dc.contributor.schoolSchool of Chemistry and Physics : Chemistryen
dc.date.issued2004en
dc.descriptionPub. No.: WO/2004/046160 International Application No.: PCT/DK2003/000788 Publication Date: 03.06.2004 International Filing Date: 18.11.2003 Chapter 2 Demand Filed: 08.06.2004 IPC: A61K 31/7088 (2006.01)en
dc.description.abstractA novel class of pharmaceuticals which comprises a Locked Nucleic Acid (LNA) which can be used in antisense therapy. These novel oligonucleotides have improved antisense properties. The novel oligonucleotides are composed of at least one LNA selected from beta-D-thio/amino-LNA or alpha-L-oxy/thio/amino-LNA. The oligonucleotides comprising LNA may also include DNA and/or RNA nucleotidesen
dc.identifier.patentPCT patent: WO 04/046160 A2, 2004en
dc.identifier.urihttp://hdl.handle.net/2440/47540
dc.source.urihttp://www.wipo.int/pctdb/en/wo.jsp?wo=2004046160en
dc.titleAmino-LNA, Thio-LNA and α-L-Oxy-LNAen
dc.title.alternativeAmino-LNA, Thio-LNA and Alpha-L-Oxy-LNAen
dc.typePatenten

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