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X-ray imaging of tumor growth in live mice by detecting gold-nanoparticle-loaded cells

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dc.contributor.authorChien, C.C.
dc.contributor.authorChen, H.
dc.contributor.authorLai, S.
dc.contributor.authorHwu, Y.
dc.contributor.authorPetibois, C.
dc.contributor.authorYang, C.
dc.contributor.authorChu, Y.
dc.contributor.authorMargaritondo, G.
dc.date.issued2012
dc.descriptionData source: Supplementary information, http://www.nature.com/scientificreports
dc.description.abstractWe show that sufficient concentrations of gold nanoparticles produced by an original synthesis method in EMT-6 and CT-26 cancer cells make it possible to detect the presence, necrosis and proliferation of such cells after inoculation in live mice. We first demonstrated that the nanoparticles do not interfere with the proliferation process. Then, we observed significant differences in the tumor evolution and the angiogenesis process after shallow and deep inoculation. A direct comparison with pathology optical images illustrates the effectiveness of this approach
dc.identifier.citationScientific Reports, 2012; 2(1):1-6
dc.identifier.doi10.1038/srep00610
dc.identifier.issn2045-2322
dc.identifier.issn2045-2322
dc.identifier.urihttps://hdl.handle.net/11541.2/115179
dc.language.isoen
dc.publisherNature Publishing Group
dc.rightsCopyright 2012 Nature Publishing Group. This work is licensed under a Creative Commons Attribution-Non Commercial-No Derivative Works 3.0 Unported License.
dc.source.urihttps://doi.org/10.1038/srep00610
dc.subjecttumor growth
dc.subjectgold-nanoparticle
dc.subjectcells
dc.titleX-ray imaging of tumor growth in live mice by detecting gold-nanoparticle-loaded cells
dc.typeJournal article
pubs.publication-statusPublished
ror.fileinfo12143156750001831 13143161730001831 9915930099601831_53134709700001831.pdf
ror.mmsid9915930099601831

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