The effect of preexisting medical comorbidities on the preeclamptic phenotype: a retrospective cohort study

Date

2021

Authors

Tanner, M.S.
De Guingand, D.
Reddy, M.
Rowson, S.
Rolnik, D.L.
Da Silva Costa, F.
Davey, M.A.
Mol, B.W.
Wallace, E.M.
Palmer, K.R.

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Journal article

Citation

Hypertension in Pregnancy, 2021; 40(4):336-345

Statement of Responsibility

Michael S. Tanner, Deborah De Guingand, Maya Reddy, Saskia Rowson, Daniel L. Rolnik, Fabricio Da Silva Costa, Mary-Ann Davey, Ben W. Mol, Euan M. Wallace, and Kirsten R. Palmer

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Abstract

Objective:To compare the effect of comorbidities on the phenotype and outcomes of preeclampsia. Methods:A matched retrospective cohort study of women delivering at a tertiary maternity center following a diagnosis of preeclampsia. We collected data on signs and symptoms, biochemical markers, and maternal and perinatal outcomes. Results:We studied 474 women; 158 women with and 316 without comorbidities. Compared to women without comorbidities, women with comorbidities delivered earlier. They suffered fewer maternal but more neonatal complications. Conclusion:Women with comorbidities receive earlier intervention than women without comorbidities, which may lead to fewer maternal complications but worse neonatal outcomes.

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Published online: 26 Oct 2021

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© 2021 Informa UK Limited, trading as Taylor & Francis Group

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