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The effect of preexisting medical comorbidities on the preeclamptic phenotype: a retrospective cohort study

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dc.contributor.authorTanner, M.S.
dc.contributor.authorDe Guingand, D.
dc.contributor.authorReddy, M.
dc.contributor.authorRowson, S.
dc.contributor.authorRolnik, D.L.
dc.contributor.authorDa Silva Costa, F.
dc.contributor.authorDavey, M.A.
dc.contributor.authorMol, B.W.
dc.contributor.authorWallace, E.M.
dc.contributor.authorPalmer, K.R.
dc.date.issued2021
dc.descriptionPublished online: 26 Oct 2021
dc.description.abstractObjective:To compare the effect of comorbidities on the phenotype and outcomes of preeclampsia. Methods:A matched retrospective cohort study of women delivering at a tertiary maternity center following a diagnosis of preeclampsia. We collected data on signs and symptoms, biochemical markers, and maternal and perinatal outcomes. Results:We studied 474 women; 158 women with and 316 without comorbidities. Compared to women without comorbidities, women with comorbidities delivered earlier. They suffered fewer maternal but more neonatal complications. Conclusion:Women with comorbidities receive earlier intervention than women without comorbidities, which may lead to fewer maternal complications but worse neonatal outcomes.
dc.description.statementofresponsibilityMichael S. Tanner, Deborah De Guingand, Maya Reddy, Saskia Rowson, Daniel L. Rolnik, Fabricio Da Silva Costa, Mary-Ann Davey, Ben W. Mol, Euan M. Wallace, and Kirsten R. Palmer
dc.identifier.citationHypertension in Pregnancy, 2021; 40(4):336-345
dc.identifier.doi10.1080/10641955.2021.1991371
dc.identifier.issn1064-1955
dc.identifier.issn1525-6065
dc.identifier.orcidMol, B.W. [0000-0001-6887-0262] [0000-0001-8337-550X]
dc.identifier.urihttps://hdl.handle.net/2440/133417
dc.language.isoen
dc.publisherInforma UK
dc.relation.granthttp://purl.org/au-research/grants/nhmrc/1113902
dc.rights© 2021 Informa UK Limited, trading as Taylor & Francis Group
dc.source.urihttps://doi.org/10.1080/10641955.2021.1991371
dc.subjectPreeclampsia; hypertension; angiogenic; complications; comorbidities
dc.titleThe effect of preexisting medical comorbidities on the preeclamptic phenotype: a retrospective cohort study
dc.typeJournal article
pubs.publication-statusPublished

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