A new bifunctional chelator for copper radiopharmaceuticals: a cage amine ligand with a carboxylate functional group for conjugation to peptides

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dc.contributor.authorMa, M.
dc.contributor.authorKaras, J.
dc.contributor.authorWhite, J.
dc.contributor.authorScanlon, D.
dc.contributor.authorDonnelly, P.
dc.date.issued2009
dc.description.abstractA new sarcophagine cage amine ligand with a pendent carboxylate functional group has been synthesised; the ligand has been conjugated to tumour targeting peptides ([Tyr3]- octreotate and [Lys3]-bombesin) and the conjugates radiolabelled with copper-64.
dc.description.statementofresponsibilityMichelle T. Ma, John A. Karas, Jonathan M. White, Denis Scanlon and Paul S. Donnelly
dc.identifier.citationChemical Communications, 2009; 14(22):3237-3239
dc.identifier.doi10.1039/B903426A
dc.identifier.issn1359-7345
dc.identifier.issn1364-548X
dc.identifier.urihttp://hdl.handle.net/2440/75155
dc.language.isoen
dc.publisherRoyal Soc Chemistry
dc.rights© The Royal Society of Chemistry 2009
dc.source.urihttps://doi.org/10.1039/b903426a
dc.subjectAnimals
dc.subjectHumans
dc.subjectCopper
dc.subjectAmines
dc.subjectCarboxylic Acids
dc.subjectPeptides
dc.subjectChelating Agents
dc.subjectCross-Linking Reagents
dc.subjectRadiopharmaceuticals
dc.subjectLigands
dc.titleA new bifunctional chelator for copper radiopharmaceuticals: a cage amine ligand with a carboxylate functional group for conjugation to peptides
dc.typeJournal article
pubs.publication-statusPublished

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