Current studentsExisting staffContact us
 

Immune protection of hepatitis B vaccine among children living in Gondar, northwest Ethiopia

Simple item page
dc.contributor.authorAyalew, G.
dc.contributor.authorAssefa, A.
dc.contributor.authorAmsalu, A.
dc.contributor.authorGeta, M.
dc.contributor.authorMihret, A.
dc.contributor.authorAseffa, A.
dc.contributor.authorHowe, R.
dc.contributor.authorAbate, E.
dc.date.issued2019
dc.description.abstractBackground: Hepatitis B virus infection is a worldwide health problem and highly endemic in developing countries including Ethiopia. Hepatitis B vaccine is included in the routine Expanded Program on Immunization since 2007 in Ethiopia. Objective: The aim of this study was to assess the sero-protection level of hepatitis B vaccination among children who have received the vaccine. Methods: A cross-sectional study was conducted among children attending Kindergarten and first cycle elementary school in Gondar town. A pre-tested structured questionnaire was used to collect the socio-demographic data. Blood sample was collected and serum separated for anti-HBs,anti-HBc and HBsAg. The data was analyzed using SPSS statistical software version 20. Binary logistic regression analysis was done. P-value less than 0.05 was considered as statistically significant. Result:Out of 431 children screened, 27 were excluded from analysis because they were positive for anti-HBc(27/431, 6.3%) and/or for HBsAg (18/431 or 4.2%). Out of 404 children, 130 (32.2%) had anti-HBs titers >10 mIU/ml (seroprotected) while 274 (68.8%) had anti-HBs titers <10 mIU/ml (non-protected).
dc.identifier.citationEthiopian Medical Journal, 2019; 57(2):137-144
dc.identifier.issn0014-1755
dc.identifier.urihttps://hdl.handle.net/11541.2/34193
dc.language.isoen
dc.publisherEthiopian Medical Association
dc.rightsCopyright 2019 The author(s).
dc.source.urihttps://emjema.org/index.php/EMJ/article/view/1211/pdf_243
dc.subjectHepatitis B virus
dc.subjectEthiopia
dc.subjectvaccination
dc.subjectchildren
dc.titleImmune protection of hepatitis B vaccine among children living in Gondar, northwest Ethiopia
dc.typeJournal article
pubs.publication-statusPublished
ror.fileinfo12271450320001831 13271450310001831 admin,+9++MS+118+(1)+(1)+edited (2)
ror.mmsid9916756124101831

Files

Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
admin,+9++MS+118+(1)+(1)+edited (2).pdf
Size:
1.08 MB
Format:
Adobe Portable Document Format
Description:
Published version
Download

Collections