The gut-brain axis in the critically ill: is glucagon-like peptide-1 protective in neurocritical care?
Date
2013
Authors
Plummer, M.
Meier, J.
Deane, A.
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Journal article
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Critical Care (UK), 2013; 17(4):163-1-163-2
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Mark P Plummer, Juris J Meier and Adam M Deane
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Abstract
Enteral nutrient is a potent glucagon-like peptide-1 (GLP-1) secretagogue. In vitro and animal studies indicate that GLP-1 has immune-modulatory and neuroprotective effects. To determine whether these immune-modulatory and neuroprotective effects of GLP-1 are beneficial in the critically ill, studies achieving pharmacological GLP-1 concentrations are warranted.
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© 2013 BioMed Central Ltd