The gut-brain axis in the critically ill: is glucagon-like peptide-1 protective in neurocritical care?

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dc.contributor.authorPlummer, M.
dc.contributor.authorMeier, J.
dc.contributor.authorDeane, A.
dc.date.issued2013
dc.description.abstractEnteral nutrient is a potent glucagon-like peptide-1 (GLP-1) secretagogue. In vitro and animal studies indicate that GLP-1 has immune-modulatory and neuroprotective effects. To determine whether these immune-modulatory and neuroprotective effects of GLP-1 are beneficial in the critically ill, studies achieving pharmacological GLP-1 concentrations are warranted.
dc.description.statementofresponsibilityMark P Plummer, Juris J Meier and Adam M Deane
dc.description.urihttp://link.springer.com/article/10.1186%2Fcc12758
dc.identifier.citationCritical Care (UK), 2013; 17(4):163-1-163-2
dc.identifier.doi10.1186/cc12758
dc.identifier.issn1466-609X
dc.identifier.issn1364-8535
dc.identifier.orcidPlummer, M. [0000-0002-9640-1911]
dc.identifier.orcidDeane, A. [0000-0002-7620-5577]
dc.identifier.urihttp://hdl.handle.net/2440/82728
dc.language.isoen
dc.publisherCurrent Science Ltd
dc.rights© 2013 BioMed Central Ltd
dc.source.urihttps://doi.org/10.1186/cc12758
dc.subjectHumans
dc.subjectEnteral Nutrition
dc.subjectImmunity, Cellular
dc.subjectIntensive Care Units
dc.subjectFemale
dc.subjectMale
dc.subjectGlucagon-Like Peptide 1
dc.titleThe gut-brain axis in the critically ill: is glucagon-like peptide-1 protective in neurocritical care?
dc.typeJournal article
pubs.publication-statusPublished

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