In silico modelling of treatment-induced tumour cell kill: Developments and advances
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(Published version)
Date
2012
Authors
Marcu, L.
Harriss-Phillips, W.
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Journal article
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Computational and Mathematical Methods in Medicine, 2012; 2012:1-16
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Loredana G. Marcu and Wendy M. Harriss-Phillips
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Abstract
Mathematical and stochastic computer (in silico) models of tumour growth and treatment response of the past and current eras are presented, outlining the aims of the models, model methodology, the key parameters used to describe the tumour system, and treatment modality applied, as well as reported outcomes from simulations. Fractionated radiotherapy, chemotherapy, and combined therapies are reviewed, providing a comprehensive overview of the modelling literature for current modellers and radiobiologists to ignite the interest of other computational scientists and health professionals of the ever evolving and clinically relevant field of tumour modelling.
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Extent: 16p.
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Copyright © 2012 Loredana G. Marcu and Wendy M. Harriss-Phillips.This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.