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In silico modelling of treatment-induced tumour cell kill: Developments and advances

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dc.contributor.authorMarcu, L.
dc.contributor.authorHarriss-Phillips, W.
dc.date.issued2012
dc.descriptionExtent: 16p.
dc.description.abstractMathematical and stochastic computer (in silico) models of tumour growth and treatment response of the past and current eras are presented, outlining the aims of the models, model methodology, the key parameters used to describe the tumour system, and treatment modality applied, as well as reported outcomes from simulations. Fractionated radiotherapy, chemotherapy, and combined therapies are reviewed, providing a comprehensive overview of the modelling literature for current modellers and radiobiologists to ignite the interest of other computational scientists and health professionals of the ever evolving and clinically relevant field of tumour modelling.
dc.description.statementofresponsibilityLoredana G. Marcu and Wendy M. Harriss-Phillips
dc.identifier.citationComputational and Mathematical Methods in Medicine, 2012; 2012:1-16
dc.identifier.doi10.1155/2012/960256
dc.identifier.issn1748-670X
dc.identifier.issn1748-6718
dc.identifier.orcidHarriss-Phillips, W. [0000-0002-2160-8723]
dc.identifier.urihttp://hdl.handle.net/2440/73523
dc.language.isoen
dc.publisherHindawi Publishing Corporation
dc.rightsCopyright © 2012 Loredana G. Marcu and Wendy M. Harriss-Phillips.This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
dc.source.urihttps://doi.org/10.1155/2012/960256
dc.subjectAnimals
dc.subjectHumans
dc.subjectNeoplasms
dc.subjectCombined Modality Therapy
dc.subjectDrug Therapy
dc.subjectArea Under Curve
dc.subjectMonte Carlo Method
dc.subjectStochastic Processes
dc.subjectKinetics
dc.subjectAlgorithms
dc.subjectModels, Theoretical
dc.subjectComputer Simulation
dc.subjectHypoxia
dc.subjectDose Fractionation, Radiation
dc.titleIn silico modelling of treatment-induced tumour cell kill: Developments and advances
dc.typeJournal article
pubs.publication-statusPublished

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