Trough concentrations of vancomycin: adult therapeutic targets are not appropriate for children

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dc.contributor.authorGordon, C.
dc.contributor.authorThompson, C.
dc.contributor.authorCarapetis, J.
dc.contributor.authorTurnidge, J.
dc.contributor.authorKilburn, C.
dc.contributor.authorCurrie, B.
dc.date.issued2012
dc.description.abstractDespite the need for effective vancomycin therapy, there are few data guiding vancomycin monitoring in children. We reviewed retrospectively vancomycin use in children 1 month to 12 years of age. Initial and adjusted target trough vancomycin concentrations in serum were infrequently achieved regardless of the dosing schedule. Currently recommended trough concentrations need to be re-examined with a more detailed pharmacokinetic study in children.
dc.description.statementofresponsibilityClaire L. Gordon, Chantelle Thompson, Jonathan R. Carapetis, John Turnidge, Charles Kilburn and Bart J. Currie
dc.identifier.citationThe Pediatric Infectious Disease Journal, 2012; 31(12):1269-1271
dc.identifier.doi10.1097/INF.0b013e31826a3eaf
dc.identifier.issn0891-3668
dc.identifier.issn1532-0987
dc.identifier.orcidTurnidge, J. [0000-0003-4240-5578]
dc.identifier.urihttp://hdl.handle.net/2440/75899
dc.language.isoen
dc.publisherLippincott Williams & Wilkins
dc.rightsCopyright: © 2012 Lippincott Williams & Wilkins, Inc.
dc.source.urihttps://doi.org/10.1097/inf.0b013e31826a3eaf
dc.subjectvancomycin
dc.subjectStaphylococcus aureus
dc.subjecttherapeutic drug monitoring
dc.titleTrough concentrations of vancomycin: adult therapeutic targets are not appropriate for children
dc.typeJournal article
pubs.publication-statusPublished

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