Epidemiology and burden of adult chronic pancreatitis in South Australia: a 20-year data linkage study

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dc.contributor.authorBampton, T.J.
dc.contributor.authorChen, J.W.
dc.contributor.authorBrown, A.
dc.contributor.authorBarnett, M.I.
dc.contributor.authorCoates, P.T.
dc.contributor.authorPalmer, L.J.
dc.date.issued2025
dc.description.abstractObjectives To investigate the epidemiology and burden of adult-onset chronic pancreatitis (CP) in South Australia. Design Retrospective case-control study; data linkage. Setting All public adult hospitals in SA. Participants Administrative data linkage from South Australia-Northern Territory DataLink was used to ascertain an index cohort of all adults with an initial diagnosis of CP aged >19 years between June 2000 and June 2019. Age- and sex-matched controls were drawn from the general population of SA, adults with type 1 diabetes mellitus and adults with type 2 diabetes mellitus (defined by International Classification of Diseases 10th Revision coding). Main outcome measures Hospital visits, days in hospital, emergency department visits, intensive care unit admissions, incidence, prevalence. Results A total of 2503 incident index cases with CP were identified. The crude prevalence and incidence were estimated as 195.1 per 100 000 and 10.4 per 100 000 per annum, respectively. Cases of CP averaged more hospital visits for any reason (median 11, IQR 5 to 21.75) than the general population (median 1, IQR 0 to 4) and had a higher healthcare burden than controls with type 1 diabetes or type 2 diabetes (all p<0.001). Indigenous individuals were over-represented in the cohort (n=358; 14.8% vs 1.5% of the general population) and had higher healthcare utilisation than other patients with CP (p<0.001). Conclusions CP is a significant burden on the SA healthcare system and was more prevalent and more burdensome in Indigenous adults. CP consumes a disproportionate level of public health services. Our findings support further research and preventive efforts, particularly in the Indigenous population.
dc.description.statementofresponsibilityTristan J Bampton, John W Chen, Alex Brown, Meghan I Barnett, P Toby Coates, Lyle John Palmer
dc.identifier.citationBMJ Open, 2025; 15(3):e089297-1-e089297-7
dc.identifier.doi10.1136/bmjopen-2024-089297
dc.identifier.issn2044-6055
dc.identifier.issn2044-6055
dc.identifier.orcidBampton, T.J. [0000-0001-7326-286X]
dc.identifier.orcidBrown, A. [0000-0003-2112-3918]
dc.identifier.orcidPalmer, L.J. [0000-0002-1628-3055]
dc.identifier.urihttps://hdl.handle.net/2440/145722
dc.language.isoen
dc.publisherBMJ Publishing Group
dc.relation.granthttp://purl.org/au-research/grants/nhmrc/GNT2011277
dc.relation.granthttp://purl.org/au-research/grants/nhmrc/1137563
dc.rights© Author(s) (or their employer(s)) 2025. Re-use permitted under CC BY. Published by BMJ Group. This is an open access article distributed in accordance with the Creative Commons Attribution 4.0 Unported (CC BY 4.0) license, which permits others to copy, redistribute, remix, transform and build upon this work for any purpose, provided the original work is properly cited, a link to the licence is given, and indication of whether changes were made. See: https://creativecommons.org/licenses/by/4.0/.
dc.source.urihttps://doi.org/10.1136/bmjopen-2024-089297
dc.subjectCase control studies; cost of illness; diabetes mellitus, Type 1; diabetes mellitus, type 2; hospitalization; information storage and retrieval; pancreatitis, chronic; middle aged; prevalence; retrospective studies; south australia; young adult
dc.subject.meshHumans
dc.subject.meshDiabetes Mellitus, Type 1
dc.subject.meshDiabetes Mellitus, Type 2
dc.subject.meshHospitalization
dc.subject.meshIncidence
dc.subject.meshPrevalence
dc.subject.meshCase-Control Studies
dc.subject.meshRetrospective Studies
dc.subject.meshCost of Illness
dc.subject.meshInformation Storage and Retrieval
dc.subject.meshAdult
dc.subject.meshAged
dc.subject.meshMiddle Aged
dc.subject.meshEmergency Service, Hospital
dc.subject.meshSouth Australia
dc.subject.meshFemale
dc.subject.meshMale
dc.subject.meshPancreatitis, Chronic
dc.subject.meshYoung Adult
dc.titleEpidemiology and burden of adult chronic pancreatitis in South Australia: a 20-year data linkage study
dc.typeJournal article
pubs.publication-statusPublished

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