Correlation of postmortem MRI and CT appearances with neuropathology in brain trauma: a comparison of two methods
Date
1998
Authors
Jones, N.
Blumbergs, P.
Brown, C.
McLean, J.
Manavis, J.
Perrett, L.
Sandhu, A.
Scott, G.
Simpson, D.
Editors
Advisors
Journal Title
Journal ISSN
Volume Title
Type:
Journal article
Citation
Journal of Clinical Neuroscience, 1998; 5(1):73-79
Statement of Responsibility
Nigel R Jones, Peter C Blumbergs, Christopher J Brown, A.Jack McLean, James Manavis, Lance V Perrett, Avinder Sandhu, Grace Scott, Donald A Simpson
Conference Name
Abstract
Postmortem magnetic resonance (MR) scans were performed on the brains of 12 victims of fatal head injuries. These were compared with neuropathological studies of the entire brain. The first six subjects were imaged with the brain in situ and comparison was also made with antemortem computed tomography (CT). The brains from the subsequent six subjects were removed at autopsy, fixed in formalin and then imaged in a mitre box designed to overcome the problems encountered in the pilot study. Although both CT and MR imaging (MRI) detected all clinically relevant haemorrhagic lesions, many pathologically significant lesions were missed. MRI detected many more lesions than CT, but still failed to visualize areas of non-haemorrhagic axonal injury.
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Dissertation Note
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Copyright © 1988 Published by Elsevier Ltd.