RANKL expression is related to the differentiation state of human osteoblasts

Date

2003

Authors

Atkins, G.
Kostakis, P.
Pan, B.
Farrugia, A.
Gronthos, S.
Evdokiou, A.
Harrison, K.
Findlay, D.
Zannettino, A.

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Journal article

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Journal of Bone and Mineral Research, 2003; 18(6):1088-1098

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Gerald J Atkins, Panagiota Kostakis, Beiqing Pan, Amanda Farrugia, Stan Gronthos, Andreas Evdokiou, Kate Harrison, David M Findlay, Andrew CW Zannettino

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Abstract

Human osteoblast phenotypes that support osteoclast differentiation and bone formation are not well characterized. Osteoblast differentiation markers were examined in relation to RANKL expression. RANKL expression was induced preferentially in immature cells. These results support an important link between diverse osteoblast functions.

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© 2003 American Society for Bone and Mineral Research

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