Calpain inhibitors and compositions

Date

2006

Authors

Abell, A.
Neffe, A.
Stuart, B.
Lee, H.
Morton, J.
Coxon, J.
Nikkel, J.
Robertson, L.
Jones, M.
Muir, M.

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Type:

Patent

Citation

Statement of Responsibility

Abell, Andrew David; Coxon, James Morriss; Miyamoto, Shigeru; Jones, Matthew Alan; Neffe, Axel Thomas; Aitken, Steven Geoffrey; Stuart, Blair Gibb; Nikkel, Janna Marie; Morton, James David; Bickerstaffe, Roy; Robertson, Lucinda Jane Goodricke; Lee, Hannah Yunyoung; Muir, Matthew Stewart

Conference Name

Abstract

Disclosed are compounds that inhibit calpains of formula I wherein X is NH, O or S and all other substituents are as described in the specification. The process for their production, and use in pharmaceutical compositions and in the treatment of prophylaxis of a disease or disorder resulting from excessive calpain activity is also disclosed.

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Dissertation Note

Provenance

Description

PATENT: Intellectual Property Office of New Zealand (IPONZ) number 547303. Filed 18 May 2007; accepted 31 August 2007.

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