The modeling of trajectories in psychotic illness
Date
2020
Authors
Clark, S.R.
Schubert, K.O.
Baune, B.
Editors
Baune, B.
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Book chapter
Citation
Personalized Psychiatry, 2020 / Baune, B. (ed./s), Ch.2, pp.3-12
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Scott R.Clark, Klaus Oliver Schubert, Bernhard T. Baune
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Abstract
The natural history of psychotic illness is one of fluctuating symptoms and functions, from prodromal illness, to first episode, to episodic relapse, and recovery or chronic illness. Recent evidence suggests that complex biological, symptomatic, and functional trajectory patterns underlie clinical presentations and outcomes. Statistical techniques for the analysis of longitudinal data have evolved to provide better estimates of trends and the determinants of growth and change for individual patients. The analysis of complex multimodal trajectories may be key to the personalization of psychosis treatment. This chapter will discuss the advantages and disadvantages of trajectory modeling techniques for psychosis research
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Copyright © 2020 Elsevier Inc. All rights reserved.