Conflicted medical journals and the failure of trust

dc.contributor.authorJureidini, J.
dc.contributor.authorMcHenry, L.
dc.date.issued2011
dc.description.abstractJournals are failing in their obligation to ensure that research is fairly represented to their readers, and must act decisively to retract fraudulent publications. Recent case reports have exposed how marketing objectives usurped scientific testing and compromised the credibility of academic medicine. But scant attention has been given to the role that journals play in this process, especially when evidence of research fraud fails to elicit corrective measures. Our experience with The Journal of the American Academy of Child and Adolescent Psychiatry (JAACAP) illustrates the nature of the problem. The now-infamous Study 329 of paroxetine in adolescent depression was negative for efficacy on all eight protocol-specified outcomes and positive for harm, but JAACAP published a report of this study that concluded that “paroxetine is generally well tolerated and effective for major depression in adolescents.” The journal's editors not only failed to exercise critical judgment in accepting the article, but when shown evidence that the article misrepresented the science, refused either to convey this information to the medical community or to retract the article.
dc.description.statementofresponsibilityJon N. Jureidini and Leemon B. McHenry
dc.identifier.citationAccountability in Research, 2011; 18(1):45-54
dc.identifier.doi10.1080/08989621.2011.542683
dc.identifier.issn0898-9621
dc.identifier.issn1545-5815
dc.identifier.orcidJureidini, J. [0000-0001-7585-2660]
dc.identifier.urihttp://hdl.handle.net/2440/68786
dc.language.isoen
dc.publisherTaylor & Francis Inc.
dc.rightsCopyright © Taylor & Francis Group, LLC
dc.source.urihttps://doi.org/10.1080/08989621.2011.542683
dc.subjectclinical trials
dc.subjectconflict of interest
dc.subjectconsumer fraud lawsuits
dc.subjectghostwriting
dc.subjectGlaxoSmithKline
dc.subjectJournal of the American Academy of Child and Adolescent Psychiatry
dc.subjectmedical journals
dc.subjectparoxetine (Paxil, Seroxat)
dc.subjectretraction
dc.subjectscientific misconduct
dc.subjectScientific Therapeutics Information
dc.subjectSmithKline Beecham
dc.titleConflicted medical journals and the failure of trust
dc.typeJournal article
pubs.publication-statusPublished

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