The Impact of Lactobacillus reuteri on Oral and Systemic Health: A Comprehensive Review of Recent Research
| dc.contributor.author | Liu, Z. | |
| dc.contributor.author | Cao, Q. | |
| dc.contributor.author | Wang, W. | |
| dc.contributor.author | Wang, B. | |
| dc.contributor.author | Yang, Y. | |
| dc.contributor.author | Xian, C.J. | |
| dc.contributor.author | Li, T. | |
| dc.contributor.author | Zhai, Y. | |
| dc.date.issued | 2025 | |
| dc.description.abstract | Oral diseases, particularly dental caries and periodontal disease, pose significant global health challenges. The imbalance of the oral microbiota plays a key role in the occurrence of these diseases, prompting researchers to seek new strategies to restore oral ecological balance. <i>Lactobacillus reuteri</i> is a Gram-positive rod-shaped bacterium that exists in various body parts of humans, including the gastrointestinal tract, urinary tract, skin, and so on. This species has a potentially positive impact on oral health and plays an important role in maintaining systemic health. Recent studies have explored the application of <i>Lactobacillus reuteri</i> in the prevention and treatment of oral diseases, and its impact on systemic health has also been preliminarily revealed. The current review summarizes the role of <i>Lactobacillus reuteri</i> in oral health and systemic health and outlines its potential applications in the future. <i>Lactobacillus reuteri</i> has shown promising prospects in treating non-communicable biofilm-dependent oral diseases, but its mechanism of action and efficacy still need further research. In addition, <i>Lactobacillus reuteri</i> has also displayed some potential benefits in promoting overall health. Future research should focus on revealing the specific pathways of action of <i>Lactobacillus reuteri</i>, screening for the most beneficial strains, determining the most effective drug delivery strategies, developing oral and systemic health products based on <i>Lactobacillus reuteri</i>, and ensuring their safety in clinical applications. | |
| dc.identifier.citation | Microorganisms, 2025; 13(1) | |
| dc.identifier.doi | 10.3390/microorganisms13010045 | |
| dc.identifier.issn | 2076-2607 | |
| dc.identifier.issn | 2076-2607 | |
| dc.identifier.orcid | Xian, C.J. [0000-0002-8467-2845] | |
| dc.identifier.uri | https://hdl.handle.net/11541.2/41596 | |
| dc.language.iso | en | |
| dc.publisher | MDPI | |
| dc.relation.funding | Foundation of Science and Technology Department of Henan Province of China | |
| dc.relation.funding | Natural Science Foundation of Education Department of Henan Province 25A320004 | |
| dc.relation.funding | Foundation of Science and Technology Department of Luoyang City of Henan Province 2101065A | |
| dc.relation.funding | Foundation of Science and Technology Department of Kaifeng City of Henan Province 2203015 | |
| dc.relation.funding | Foundation of Key Lab of Medical Molecular Cell Biology of Shanxi Province and Shanxi University MMCB-OP-2023-03 | |
| dc.relation.funding | Foundation for Young Scholar in School of Stomatology of Henan University HUSSYS2024005 | |
| dc.rights | Copyright 2024 by the authors.Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license. (https://creativecommons.org/licenses/by/4.0/) | |
| dc.source.uri | https://doi.org/10.3390/microorganisms13010045 | |
| dc.subject | Lactobacillus reuteri | |
| dc.subject | dental caries | |
| dc.subject | gastrointestinal diseases | |
| dc.subject | microbiome | |
| dc.subject | oral mucosal diseases | |
| dc.subject | periodontal diseases | |
| dc.title | The Impact of Lactobacillus reuteri on Oral and Systemic Health: A Comprehensive Review of Recent Research | |
| dc.type | Journal article | |
| pubs.publication-status | Published | |
| ror.fileinfo | 12298045380001831 13298045370001831 Open Access Published Version | |
| ror.mmsid | 9916939742201831 |
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